422 Asymptomatic severe aortic stenosis: is there a role of BNP in decision making?
نویسندگان
چکیده
منابع مشابه
Role of BNP in patients with severe asymptomatic aortic stenosis.
Senile degenerative valvular aortic stenosis affects approximately 2% of the population over the age of 65. Aortic stenosis impedes left ventricular emptying and increases left ventricular wall stress, which leads to elevation of brain natriuretic peptide (BNP) levels. Aortic stenosis progresses slowly, allowing the left ventricle to develop concentric hypertrophy, which normalizes wall stress....
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The management of asymptomatic patients with severe aortic stenosis is challenging. Unfortunately, evaluation of symptoms such as dyspnoea remains subjective. The use of exercise echocardiography may help to predict major events in patients with asymptomatic severe aortic stenosis. This article explains how to perform the test and discusses which echocardiographic measurements should be obtaine...
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Methods Transthoracic echocardiography and measurement of B-type natriuretic peptide level from venous blood sample were performed in 150 consecutive patients with asymptomatic severe AS and normal exercise test. Patients were classified in 4 groups, depending on left ventricular flow state (normal flow [NF] vs. low flow [LF]: 35 ml/m) and pressure gradient levels (low gradient [LG] vs. high gr...
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The management and the clinical decision making in asymptomatic patients with aortic stenosis are challenging. An "aggressive" management, including early aortic valve replacement, is debated in these patients. However, the optimal timing for surgery remains controversial due to the lack of prospective data on the determinants of aortic stenosis progression, multicenter studies on risk stratifi...
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Patients with symptomatic severe aortic stenosis (AS) benefit from aortic valve replacement surgery, but the management of patients with asymptomatic severe AS is more controversial. While cholesterol and angiotensin have been linked to AS progression, we should await the results of ongoing randomized trials before medical therapy to lower cholesterol or inhibit angiotensin can be recommended t...
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ژورنال
عنوان ژورنال: European Journal of Echocardiography
سال: 2006
ISSN: 1525-2167
DOI: 10.1016/s1525-2167(06)60212-6